So-called intracranial germ cell tumours: are they really of germ cell origin?

摘要: We have studied 139 cases of intracranial germ cell tumours up to the beginning 1993, 63.3% which showed monotypic histological patterns and 36.7% were shown be mixed tumours. All these underwent surgery followed by radiation and/or chemotherapy. choriocarcinoma died within 2 years. Cases yolk sac tumour (endodermal sinus tumour) embryonal carcinoma also poor results. Mature teratoma had a 5-year survival rate (5 YSR) 10-year (10 92.9% each. Immature malignant 5-YSR 10-YSR 75.0% Germinoma 94.7% 91.2%. results may bring into question validity theory, since germinoma, should most undifferentiated according was benign differentiated, in follow-up study. Therefore, not originate from one single type cells (primordial germs cells), except for germinoma. The embryonic various stages embryogenesis perhaps misplaced bilaminar disc become involved stream lateral mesoderm at time primitive streak formation carried future cranial area wrongly enfolded brain neural tube formation. following law propounded: Tumours composed resembling appearing earlier (ontogenesis) are more than those later (ontogenesis).