Proteolytic Degradation of Silk Fibroin Scaffold by Protease XXIII

摘要: Two-dimensional silk scaffolds were directly spun on the glass plates by Bombyx mori (called locally Nang- Lai) silkworms and used as subject for proteolytic degradation study with protease XXIII. The incu- bated enzyme solution at 37 °C up to 10 weeks. Those of scaffold properties: surface morphology, secondary structure, mass loss, ratios particle sizes investigated. Silk fibroin slightly changed their structure after exposure protease. They also loose greater than 20% end incubation periods. Much was quickly during 4 weeks scattering between 1 15 μm found. results suggested that XXIII is an which could be degraded fibroin. Therefore, it will this model or preparing material further applications.