Resorbable polymer fibers for ligament augmentation.

摘要: Resorbable augmentation devices for cruciate ligament surgery have been developed to temporarily protect healing tendon grafts or sutured ligaments against high tensile loads during the postoperative period. Materials available at present [e.g., polydioxanone (PDS)] show a half-life strength of only 4-6 weeks, whereas process revitalization and recovering transplanted graft can take up 12 months. Therefore, device that provides gradually decreasing mechanical properties with half-time least 6 months would be desirable. In order obtain suitable material, we investigated degradation kinetics variety different resorbable fibers made poly(L-lactide) poly(L-lactide-co-glycolide). The fiber materials differed in processing treatment parameters like thermal posttreatment, irradiation, diameter. were degraded vitro tested molecular weight various time points 72 weeks. ranged between 5 64 depending on their parameters. contrast, stiffness did not decrease adequately. However, an does change much versus could provide gradual increase load, which is important stimulate orientation collagenous tissue. design construct braided out more than one quickly degrading suggested. After breakdown faster-degrading components automatically by diminution load-carrying volume.