Paroxysmal dysarthria-ataxia syndrome: Literature review on MRI findings and report of a peculiar case with clinically isolated syndrome coexisting with anti-N-methyl-d-aspartate receptor antibodies.

摘要: Paroxysmal dysarthria and ataxia (PDA) syndrome constitutes a rare neurological disorder, is generally reported in cases of multiple sclerosis (MS) involving the midbrain. We present an illustrative case 32-year-old female who developed clinically isolated manifested paroxysmal dysarthria, ataxia, ptosis diplopia, coexisting with anti-N-methyl-d-aspartate receptor antibodies. review literature identify 23 other brain MRI examinations to summarize lesion locations clinical characteristics PDA syndrome, ultimately provide new framework for understanding this condition. The current expands spectrum symptoms which was including but not limited ataxia. Caudal paramedian midbrain lesions decussation superior cerebellar peduncles appear be critical syndrome.