Induction of thymidine−3h incorporation in multinucleated myotubes by rous sarcoma virus

摘要: During the differentiation of skeletal muscle, mononucleated myoblasts fuse to form multinucleated myotubes. After fusion, both DNA synthesis and nuclear division cease. When clones chick embryonic leg muscle consisting myotubes are infected with Rous sarcoma virus, (as measured by thymidine-3H incorporation) is induced in nuclei within 24 hours. On other hand, not reactivated. These findings indicate that restriction which attends formation irreversible since RSV, an RNA reactivates mature myotubes. Induction, Par le Virus du Sarcome de Rous, L'incorporation Thymidine Tritiee dans la Fibre Musculaire Striee Pendant des muscles squelette, les myoblastes mononuclees fusionnent pour donner fibres musculaires multinucleees. Apres synthese d'ADN et noyau cessent. Si l'on infecte, avec virus sarcome patte d'embryon poulet composes a fois myeloblastes musculaires, l'ADN (mesuree par incorporation thymidine tritiee) est provoquee noyaux heures. contre, nucleaire n'est pas reactivee. Ces observations montrent que l'arrět qui accompagne puisque (qui appartient au groupe ARN) reactive cette arrivees maturite.