Mass spectrometry based lipid(ome) analyzer and molecular platform: a new software to interpret and analyze electrospray and/or matrix-assisted laser desorption/ionization mass spectrometric data of lipids: a case study from Mycobacterium tuberculosis.
作者： Varatharajan Sabareesh , Gurpreet Singh
DOI: 10.1002/JMS.3163
关键词:
摘要: Mass Spectrometry based Lipid(ome) Analyzer and Molecular Platform (MS-LAMP) is a new software capable of aiding in interpreting electrospray ionization (ESI) and/or matrix-assisted laser desorption/ionization (MALDI) mass spectrometric data lipids. The graphical user interface (GUI) this standalone programme built using Perl::Tk. Two databases have been developed constituted within MS-LAMP, on the basis Mycobacterium tuberculosis (M. tb) lipid database (www.mrl.colostate.edu) that Lipid Metabolites Pathways Strategy Consortium (LIPID MAPS; www.lipidmaps.org). Different types queries entered through GUI would interrogate with chosen database. can be molecular mass(es) or mass-to-charge (m/z) value(s) formula. LIPID MAPS identifier also used to search but not for M. tb Multiple choices provided select diverse ion Satisfying input parameters, glimpse various categories their population distribution viewed output. Additionally, structures lipids output seen ChemSketch (www.acdlabs.com), which has linked programme. Furthermore, version MS-LAMP use Linux operating system separately available, wherein PyMOL view result as from General Lipidome MS-LAMP. The utility demonstrated ESI extracts grown under two different pH (5.5 7.0) conditions. Copyright © 2013 John Wiley & Sons, Ltd.
harvard.edu
sci-hub.se 参考文章(37)
Xianlin Han, David M. Holtzman, Daniel W. McKeel, John Kelley, John C. Morris, Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis Journal of Neurochemistry. ,vol. 82, pp. 809- 818 ,(2002) , 10.1046/J.1471-4159.2002.00997.X
H Alex Brown, Robert C Murphy, Working towards an exegesis for lipids in biology Nature Chemical Biology. ,vol. 5, pp. 602- 606 ,(2009) , 10.1038/NCHEMBIO0909-602
Eric Maréchal, Mickaël Riou, Dominique Kerboeuf, Frédéric Beugnet, Pierre Chaminade, Philippe M. Loiseau, Membrane lipidomics for the discovery of new antiparasitic drug targets. Trends in Parasitology. ,vol. 27, pp. 496- 504 ,(2011) , 10.1016/J.PT.2011.07.002
William J. Griffiths, Tandem mass spectrometry in the study of fatty acids, bile acids, and steroids. Mass Spectrometry Reviews. ,vol. 22, pp. 81- 152 ,(2003) , 10.1002/MAS.10046
Tomáš Pluskal, Sandra Castillo, Alejandro Villar-Briones, Matej Orešič, MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data BMC Bioinformatics. ,vol. 11, pp. 395- 395 ,(2010) , 10.1186/1471-2105-11-395
Ronny Herzog, Kai Schuhmann, Dominik Schwudke, Julio L. Sampaio, Stefan R. Bornstein, Michael Schroeder, Andrej Shevchenko, LipidXplorer: A Software for Consensual Cross-Platform Lipidomics PLoS ONE. ,vol. 7, pp. e29851- ,(2012) , 10.1371/JOURNAL.PONE.0029851
Fong-Fu Hsu, Kristina Soehl, John Turk, Albert Haas, Characterization of mycolic acids from the pathogen Rhodococcus equi by tandem mass spectrometry with electrospray ionization. Analytical Biochemistry. ,vol. 409, pp. 112- 122 ,(2011) , 10.1016/J.AB.2010.10.006
Haowei Song, Fong-Fu Hsu, Jack Ladenson, John Turk, Algorithm for Processing Raw Mass Spectrometric Data to Identify and Quantitate Complex Lipid Molecular Species in Mixtures by Data-Dependent Scanning and Fragment Ion Database Searching Journal of the American Society for Mass Spectrometry. ,vol. 18, pp. 1848- 1858 ,(2007) , 10.1016/J.JASMS.2007.07.023
Eva-Maria Hein, Bertram Bödeker, Jürgen Nolte, Heiko Hayen, Software tool for mining liquid chromatography/multi-stage mass spectrometry data for comprehensive glycerophospholipid profiling. Rapid Communications in Mass Spectrometry. ,vol. 24, pp. 2083- 2092 ,(2010) , 10.1002/RCM.4614
C Barry, Interpreting cell wall 'virulence factors' of Mycobacterium tuberculosis Trends in Microbiology. ,vol. 9, pp. 237- 241 ,(2001) , 10.1016/S0966-842X(01)02018-2