Silent ischemia in unstable angina is related to an altered cardiac norepinephrine handling.
作者： G G Neri Serneri , M Boddi , L Arata , C Rostagno , P Dabizzi
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摘要: BACKGROUNDInferential evidence suggests that silent ischemia might be related to sympathetic activity. Study of [3H]norepinephrine kinetics is a suitable tool assess the regional This method was applied investigate whether myocardial in unstable angina and depends on cardiac overactivity.METHODS AND RESULTSPatients with active were compared patients inactive angina, stable effort controls. Silent evaluated by three 24-hour Holter monitoring periods alternate days, assessed under rest conditions following cold pressor test. Simultaneously, catecholamine concentrations measured aortic, coronary sinus, peripheral venous blood. Different than other groups (p = 0.0013), majority ischemic episodes occurred without increase heart rate. These ...
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