Conjugation, Transport, and Elimination of Drugs in Humans
作者： Ronald E. Savage
DOI: 10.1002/9780470921920.EDM121
关键词:
摘要: This article reviews the conjugation, transport, and elimination of drugs in humans. Drug-conjugating enzymes discussed include UGTs, SULTs, GSTs, MTs, NATs. In addition, excretion humans role transport proteins their relationship to conjugated metabolites as well NRs governing expression DMEs are presented. Finally, factors that impact summarized including drug–drug interactions, dietary phytochemicals herbal supplements, intrinsic such genetics, gender, age. Keywords: human; conjugative metabolism; transport proteins; elimination; excretion
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