Influence of Systolic and Diastolic Blood Pressure on the Risk of Incident Atrial Fibrillation in Women
作者： David Conen , Usha B. Tedrow , Bruce A. Koplan , Robert J. Glynn , Julie E. Buring
DOI: 10.1161/CIRCULATIONAHA.108.830042
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摘要: Background— The influence of systolic and diastolic blood pressure (BP) on incident atrial fibrillation (AF) is not well studied among initially healthy, middle-aged women. Methods Results— A total 34 221 women participating in the Women’s Health Study were prospectively followed up for AF. risk AF across categories BP was compared by use Cox proportional-hazards models. During 12.4 years follow-up, 644 events occurred. Using measurements at baseline, we discovered that long-term significantly increased BP. Multivariable-adjusted hazard ratios (<120, 120 to 129, 130 139, 140 159, ≥160 mm Hg) 1.0, 1.00 (95% CI, 0.78 1.28), 1.28 1.63), 1.56 1.22 2.01), 2.74 1.77 4.22) (P trend <0.0001). Adjusted baseline (<65, 65 74, 75 84, 85 89, ...
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