Is It Safe to Prevent and Treat Postmenopausal Osteoporosis

摘要: Osteoporosis is a major health problem, and various treatment options are available to prevent fractures. The efficacy of most therapies similar, but costs vary enormously adverse effects seen with all treatments. HRT the optimal for prevention postmenopausal osteoporosis in terms efficacy, safety, cost. risks this have been overstated far outweighed by benefits. This should be considered as first-line therapy prevention. Bisphosphonates an effective alternative established osteoporosis. They associated number including atrial fibrillation, osteonecrosis jaw, fragility fractures femoral shaft. Whether other will emerge long term remains seen, their skeletal retention time caution against use younger patients. Denosumab new that has convenient dosing schedule not retained skeleton. It powerful anti-resorptive effect thus carries same jaw shaft bisphosphonates. Other treatments less or either withdrawn (calcitonin) limited (strontium ranelate) because effects.