Cough aerosol in healthy participants: fundamental knowledge to optimize droplet-spread infectious respiratory disease management

摘要: The Influenza A H1N1 virus can be transmitted via direct, indirect, and airborne route to non-infected subjects when an infected patient coughs, which expels a number of different sized droplets the surrounding environment as aerosol. objective current study was characterize human cough aerosol pattern with aim developing standard bioaerosol model for Pandemic control. 45 healthy non-smokers participated in open bench by giving their best effort cough. laser diffraction system used obtain accurate, time-dependent, quantitative measurements size expelled Voluntary coughs generated ranging from 0.1 - 900 microns size. Droplets less than one-micron represent 97% total measured contained Age, sex, weight, height corporal mass have no statistically significant effect on composition terms droplets. We developed model. quantitatively characterized pattern, size, present most important mode person-to-person transmission IRD: bioaerosol. Small (< 1 μm) predominated coughing. is single source indirect and/or respiratory infections like virus. Open bench, Observational, Cough, Aerosol