The Role of Microaggregation in Hormone–Receptor–Effector Interactions

摘要: Publisher Summary The binding of a hormone, neurotransmitter, or other ligand that is active at very low concentrations to highly specific receptors an interaction fundamental importance for the regulation cell function. It has become evident formation ligand–receptor complex only first step in series events lead production one more second messengers. intermediate steps include with coupling factors, such as activating and inhibitory proteins mediate between various adenylate cyclase dimerization receptor–hormone complex. Receptor involved ability antireceptor antibodies mimic biological actions number hormones including some, insulin, which messenger not yet been identified. analyzes system regulatory protein mediates interactions receptor effector.