Methods of diagnosing and treating parp-mediated diseases

作者: Valeria S. Ossovskaya , Barry M. Sherman

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摘要: Disclosed are methods of identifying a disease treatable with modulators differentially expressed genes in disease, including at least PARP modulators, by the level expression genes, PARP, plurality samples from population, making decision regarding to wherein is made based on genes. The method can further comprise treating subject population identified relate up-regulated differentially-expressed and treatment disease. also help determining efficacy

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