摘要: Chronic kidney disease (CKD) is a worldwide public health issue. In the United States there rising incidence and prevalence of failure with poor outcomes high cost. Most chronic nephropathies are characterized by progressive course that leads, at variable rate, to loss function need for renal replacement therapy. The progression CKD typically moves through phases from initial diminution reserve mild, moderate severe reductions in glomerular filtration rate (GFR), end-stage (ESRD). There growing evidence some adverse can be prevented or delayed preventive measures, early detection treatment.