Single Deranged Physiologic Parameters Are Associated With Mortality in a Low-Income Country

作者: Tim Baker , Jonas Blixt , Edwin Lugazia , Carl Otto Schell , Moses Mulungu

DOI: 10.1097/CCM.0000000000001194

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摘要: Objective: To investigate whether deranged physiologic parameters at admission to an ICU in Tanzania are associated with in-hospital mortality and compare single a more complex scoring system. Design: Prospective, observational cohort study of patient notes records. Data were collected on vital signs the ICU, characteristics, outcomes. Cutoffs for defined priori their association was analyzed using multivariable logistic regression. Setting: Muhimbili National Hospital, Dar es Salaam, Tanzania. Patients: All adults admitted 15-month period. Measurements Main Results: Two hundred sixty-nine patients included: 54% female, median age 35 years. In-hospital 50%. At admission, 69% had one or parameter. Sixty-four percent parameter died hospital compared 18% without (p < 0.001). The presence (adjusted odds ratio, 4.64; 95% CI, 1.95-11.09). Mortality increased increasing number (odds ratio per parameter, 2.24 [1.53-3.26]). Every individual unadjusted ratios between 1.92 16.16. A Early Warning Score greater than equal 7 2.51 [1.23-5.14]). Conclusion: Single critically ill population low-income country. As measure illness severity, as useful compound system this setting could be termed danger signs. Danger may suitable basis routines identify treat patients.

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