Pathogenesis of Adolescent Idiopathic Scoliosis.

摘要: Understanding the cause of adolescent idiopathic scoliosis is important for elucidating its pathogenesis. Epidemiological investigations have demonstrated that incidence approximately 2% in patients with a Cobb angle 20°. The proportion who are need treatment only 0.1% to 0.3%. wide range curve magnitudes suggests presence multiple genetic and environmental factors1-3. Various theories been proposed regarding scoliosis, but none widely accepted3. Based on historical recent findings present report reviews muscular theory, neurological connective tissue bone growth mismatch experimental animal models this disorder. The most representative theory was based electromyographic Le Febvre et al.4. That study revealed potential asymmetry erector …