Advanced precancerous lesions (APL) in the colonic mucosa.

摘要: Colorectal cancer is a leading cause of death worldwide. Most colorectal cancers are preventable. Surveillance colonoscopy used to detect and remove precancerous lesions. Although the majority lesions develop sporadically, some have an inherited component. In this review, we summarize clinical, pathologic, molecular features advanced colon. The most common clinically important intestinal polyposis syndromes, their genetics, also discussed. Finally, current recommendations regarding treatment surveillance lesions, both in sporadic setting, reviewed.