GENETIC VARIATION IN NATURAL KILLER (NK) ACTIVITY IN THE RAT

摘要: Publisher Summary This chapter focuses on immunogenetic factors that play an important role in determining the levels of vitro and vivo natural killer (NK) activity. The results demonstrate a variety genetic may be NK levels. Results suggest although do rats, but genetics these control mechanisms are not clear. With exception BN there was very little decline either numbers or activity with age. Only homozygous nudes (rnu/rnu) were found to have high mechanism by which this is achieved seems through increase percentage large granular lymphocytes (LGL) effector cells. ability identify cells rat observed variation their cytotoxic should provide sound basis for further analysis low strains nature.