Severe combined immunodeficiency with thymic mast cell hyperplasia.

摘要: The autopsy finding on an infant with severe combined immunodeficiency was marked thymic mast cell hyperplasia. clinical immune status showed a deficit in T (thymus derived) lymphocytes and low immunoglobulin levels. the histologic pattern designated alymphoplasia lack of development reticuloendothelial organs. hyperplasia may be result antigenic stimulus early embryonic life and/or differentiation at expense normal lymphoid caused by genetic defect.