Natural History of Thyroid Eye Disease

摘要: Thyroid eye disease (TED) is an autoimmune disorder causing inflammation, expansion, and occasionally fibrosis of orbital fat muscle. In most cases, the presents with a gradual onset proptosis lid retraction, typically associated expansion on imaging. approximately one third follows more fulminant course significant involvement or extraocular muscles consequent periocular soft tissue congestion, motility disruption, and/or optic nerve compression. The resulting clinical changes may cause cosmetic functional morbidity are graded as severity. TED biphasic active, progressive phase followed by quiescent, stable phase; this activity. Various evaluation systems exist for including Werner’s NO SPECS European Group Graves’ Orbitopathy (EUGOGO) severity scales, Clinical Activity Score (CAS), VISA classification recording forms Understanding natural history helps in earlier diagnosis, identification those at risk serious consequences, choosing appropriate therapy.