Analysis of selected risk factors for nodal metastases in head and neck cutaneous squamous cell carcinoma

摘要: Cutaneous squamous cell carcinoma (cSCC) accounts for 20 % of all skin malignancies and deaths. In contrast to mucosal SCC, treatment results are very good. However, regional metastases present in 5–20 % cases, the prognosis patients with is 50 % lower. It has been reported that several risk factors responsible head neck lymph node metastasis, such as: poor differentiation, local recurrence, immunosuppression, tumour dimension. Multivariate analysis metastatic lesions cSCC. Retrospective treated at our department The study includes 100 patients: 66 males (66 %) 34 females (34 %), aged 26–98 years (mean age 74.6). was evaluated for: sex predilection, stage (according 7th edition American Joint Committee on Cancer TNM staging), site. Most (79 cases; 79 %) were primary cSCC, while other 21 presented recurrence Neck diagnosed five cSCC three recurrent No distant metastasis observed. most common location auricle (29 29 %). dissection performed frequently lip tumours (17/22 77 %). often (2 patients) buccal region patients). (25/66 38 %) whereas nasal regions locations, 8 each (8/34 23 %). 20 (30 %) 12 (35 %). confirmed 5 (15 %) 3 (5 %). histopathological G2 (57 57 %). Of eight four had poorly-differentiated (histopathological G3). Thus, 4 24 (17 %) G3 experienced metastasis. Our findings suggest as degree dimension and/or location, can increase metastases. For this reason, factors, should be considered evaluate lesions.