Shock Index as a Predictor of Myocardial Damage and Clinical Outcome in ST-Elevation Myocardial Infarction.

作者: Sebastian J Reinstadler , Georg Fuernau , Charlotte Eitel , Suzanne de Waha , Steffen Desch

DOI: 10.1253/CIRCJ.CJ-15-1135

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摘要: BACKGROUND Data on the prognostic value of shock index in patients with ST-elevation myocardial infarction (STEMI) are scarce. Furthermore, relationship damage is unknown. The aim this study was to evaluate association markers and clinical outcome STEMI. METHODS AND RESULTS This multicenter analyzed 791 patients. Patients were categorized 2 groups according admission (optimized cut-off=0.62). Infarct severity determined by cardiac magnetic resonance (CMR) imaging. cardiogenic that unable undergo CMR acquisition excluded. Major adverse events (MACE) defined as a composite death, reinfarction congestive heart failure within 12 months. elevated (n=321 [40.6%]) had significantly larger area-at-risk (37.6 [27.8-50.4] % left ventricular volume [LV] vs. 34.3 [24.5-46.0] LV, P=0.02), infarct size (19.5 [10.7-28.0] LV 14.9 [7.7-22.3] P<0.001), lower salvage (46.2 [27.9-64.5] 53.5 [36.5-75.2], extent microvascular obstruction (0.3 [0.0-2.2] 0.0 [0.0-1.4] P=0.01). An associated reduced MACE-free survival (P<0.001). identified an independent predictor MACE (hazard ratio=2.92 [1.24-4.22], P<0.01). CONCLUSIONS STEMI more pronounced damage. Moreover, independently at

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