Decision-making value of nuclear dense fine speckled pattern in systemic autoimmune rheumatic disease: trick or treat?
作者： Chuiwen Deng , Xiaohui Qu , Shaoyun Cheng , Xiaofeng Zeng , Yongzhe Li
DOI: 10.1136/ANNRHEUMDIS-2019-215587
关键词:
摘要: We read with great interest the recommendation published by Damoiseaux et al and other members of International Consensus on Antinuclear antibody (ANA) patterns (ICAP).1 Not only clinical relevance human epithelial type 2 (HEp-2) indirect immunofluorescent (IIF) was presented, suggestion about follow-up testing also given in this article, which will benefit decision-making daily practice. Nuclear dense fine speckled (DFS) pattern, a competent-level pattern evaluated ICAP previously (AC-02),2 is frequently discussed current for it being best associated apparently healthy individuals, or negatively correlating systemic autoimmune rheumatic disease (SARD). Damoiseaux demonstrated that negative relationship between DFS SARD be valid if both specific DFS70 common extractable nuclear antigen (ENA) autoantibodies were not observed.1 However, strategies remains controversy. Some proposed should detected after screening IIF, as suggested …
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