Medroxyprogesterone Acetate (Depo-Provera)

摘要: Members of the American Academy Pediatrics have asked Committee on Drugs to comment efficacy and indications for use injectable progestin, medroxyprogesterone acetate (Depo-Provera), in adolescents. The has reviewed available data about drug assembled several possible its found no conclusive evidence that Depo-Provera is harmful humans, it acknowledges there controversy potential, undesirable, long-term effects cannot be resolved by extant data. also wishes state lack availability as an approved contraceptive agent hinders provision care needed some adolescents United States. believes Depo-Provera—or a similar, long-acting agent—can invaluable small, well defined group who need effective contraception are unable benefit from other methods. They may at risk participating sexual activity unknowingly or unwillingly, sexually active choice. Some these intellectually impaired pregnancy especially unwanted. Conventional oral difficult retarded teen-agers. If adult will responsible administering contraceptives protecting vulnerable adolescent advances her own inability estimate consequences unprotected intercourse, warranted. Menstrual flow creates major emotional disturbance hygienic problem small number (or their caretakers), cessation menstrual function—so often resulting continued Depo-Provera—may desirable side effect.