Deoxynucleotide-polymerizing Enzymes of Calf Thymus Gland

作者: Lucy M.S. Chang , G.R. Cassani , F.J. Bollum

DOI: 10.1016/S0021-9258(19)44583-3

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摘要: Abstract Replication of polydeoxyadenylate and polydeoxythymidylate catalyzed by the high molecular weight DNA polymerase proceeds only in presence a complementary oligodeoxynucleotide. The oligodeoxynucleotide initiator chain must be greater than 6 nucleotides for poly(dA) replication 5 poly(dT) replication. oligonucleotide is incorporated into product chains. When multiplicity chains are present (more 1 per template) then several grow simultaneously on each template. structure distribution products may predicted from to template ratio.

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