A comparison of associated enzyme activities in various deoxyribonucleic acid polymerases.
作者： Lucy M.S. Chang , F.J. Bollum
DOI: 10.1016/S0021-9258(19)43942-2
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摘要: Abstract A comparison of activities associated with Escherichia coli polymerase I, calf thymus 6 to 8 S DNA and 3.4 demonstrates that neither exonuclease activity nor pyrophosphorolysis is essential for polymerization. The enzyme has no demonstrable 3'- 5'-exonuclease cannot carry out pyrophosphate exchange. Under these conditions phosphodiester bond formation kinetically irreversible.
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