Serum fatty acid proportions are altered during the year following acute Epstein-Barr virus infection

摘要: Because abnormal serum fatty acid (FA) proportions had been found at three months after infectious mononucleosis (IM) in a pilot study, total FA profiles of 20 normal college students were measured monthly intervals for one year following an acute Epstein-Barr virus (EBV) infection. Below arachidonic and reversal the usual ratio linoleic oleic acids maximal during third month IM. These abnormalities coincided with symptom increased physical malaise, despite apparent clinical recovery, common Persistence low content beyond six postinfection occurred all seven who showed continued symptoms. Estimation enzyme activities over post-IM suggested that elongation function was normal, but desaturation lower than particularly early EBV An inability host to normalize linoleic/oleic may parallel delayed recovery from infection offer insight into its pathogenesis.