Colloidal systems for drug delivery: from design to therapy
作者： Mariana Beija , Robert Salvayre , Nancy Lauth-de Viguerie , Jean-Daniel Marty
DOI: 10.1016/J.TIBTECH.2012.04.008
关键词:
摘要: Nanomedicine, or medicine using nanometric devices, has emerged in the past decade as an exhilarating domain that can help to solve a number of problems linked unsatisfactory therapeutic responses so-called 'old drugs'. This dissatisfaction stems from inadequate biodistribution after drug's application, which leads limited response but also numerous side effects healthy organs. The drugs encapsulated nano object will act vector be modified tune its efficacy. review provides general overview existing colloidal nanovectors: liposomes, polymeric micelles, vesicles, nanoparticles (NPs), and dendrimers. We describe their characteristics, advantages drawbacks, discuss use treatment various diseases.
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