Detection and Cellular Localization of Lead by Electron Probe Analysis in the Diagnosis of Suspected Lead Poisoning in Rhesus Monkeys

作者: Bernard Sass , William G. Banfield , Umberto Saffiotti

DOI: 10.1177/019262339101900104

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摘要: Lead poisoning of unknown source was diagnosed histologically in 2 rhesus monkeys (Macaca mulatta) by finding acid-fast intranuclear inclusion bodies the epithelial cells renal cortical tubules. The presence lead inclusions determined scanning electron microscopy/energy dispersive x-ray analysis using sections from paraffin embedded tissues. This observation indicates usefulness this technique for detection and cellular localization tissues, even archival material.

参考文章(21)
Michael T. Taussig, The Nervous System ,(1991)
André Läuchli, Electron Probe Analysis Springer, Berlin, Heidelberg. pp. 191- 236 ,(1972) , 10.1007/978-3-642-87496-3_8
R.A. Goyer, B.C. Rhyne, Pathological effects of lead. Experimental pathology. ,vol. 12, pp. 1- 77 ,(1973)
D. J. White, Histochemical and histological effects of lead on the liver and kidney of the dog. British journal of experimental pathology. ,vol. 58, pp. 101- ,(1977)
D F Vandeputte, W A Jacob, R E Van Grieken, Influence of fixation procedures on the microanalysis of lead-induced intranuclear inclusions in rat kidney Journal of Histochemistry and Cytochemistry. ,vol. 38, pp. 331- 337 ,(1990) , 10.1177/38.3.2154517
B. C. ZOOK, R. M. SAUER, F. M. GARNER, LEAD POISONING IN CAPTIVE WILD ANIMALS Journal of Wildlife Diseases. ,vol. 8, pp. 264- 272 ,(1972) , 10.7589/0090-3558-8.3.264
FS Hsu, L Krook, JN Shively, JR Duncan, WG Pond, None, Lead Inclusion Bodies in Osteoclasts Science. ,vol. 181, pp. 447- 448 ,(1973) , 10.1126/SCIENCE.181.4098.447
B.J. McLeavey, Lead poisoning in dogs New Zealand Veterinary Journal. ,vol. 25, pp. 395- 396 ,(1977) , 10.1080/00480169.1977.34466
KENNETH G. CARROLL, FRANCO R. SPINELLI, ROBERT A. GOYER, Electron probe microanalyser localization of lead in kidney tissue of poisoned rats. Nature. ,vol. 227, pp. 1056- 1056 ,(1970) , 10.1038/2271056A0
Stanley L. Robbins, Ramzi S. Cotran, Pathologic basis of disease ,(1974)