Neural mechanisms for response selection: comparing selection of responses and items from working memory.

摘要: Abstract Recent functional imaging studies of working memory (WM) have suggested a relationship between the requirement for response selection and activity in dorsolateral prefrontal (DLPFC) parietal regions. Although number WM operations are likely to occur during selection, current study was particularly interested contribution this neural network WM-based when compared an item from list being maintained memory, verbal learning task. The design manipulated stimulus–response mappings so that selecting not always accompanied with motor response. Functional activation supported previous findings fronto-parietal involvement, although contrast left, rather than right, DLPFC significantly more active memory-guided response, currently or executing Our results contribute debate over role tasks, suggesting appears related potentially supporting hypothesized biasing attention toward task-relevant material posterior