Magnetoencephalographic signatures of right prefrontal cortex involvement in response inhibition

摘要: The prefrontal cortex has a pivotal role in top-down control of cognitive and sensory functions. In complex go-nogo tasks, the right dorsolateral is considered to be important for guiding response inhibition. However, little known about temporal dynamics neurophysiological nature this activity. To address issue, we recorded magnetoencephalographic brain activity 20 women during visual task. showed an increase amplitude event-related fields induced alpha frequency band nogo comparison go trials. peak preceded mean reaction time around 360 ms trials, thus supports proposed gating inhibition further suggests that might involved gating. results were similar both successful unsuccessful these conditions, instead observed pre- poststimulus differences occipital central areas. Thus, seemed additionally depend on prestimulus anticipatory desynchronization areas as it was reduced prior conclusion, suggest functional by synchronization not only sensory, but also Hum Brain Mapp 35:5236–5248, 2014. © 2014 Wiley Periodicals, Inc.