Visuomotor Activation of Inhibition-Processing in Pediatric Obsessive Compulsive Disorder: A Magnetoencephalography Study
作者： Eman Nishat , Colleen Dockstader , Anne L. Wheeler , Thomas Tan , John A. E. Anderson
DOI: 10.1101/2020.11.23.394841
关键词:
摘要: Background: The ability to inhibit a response is component of executive control that impaired in many individuals with obsessive compulsive disorder (OCD) and may contribute clinical symptoms. This study explored whether neural processing during inhibition, measured using magnetoencephalography (MEG), differed sample medication-naive youth OCD, compared typically developing controls (TDC). Methods: Data was acquired from 20 children OCD (11.9 {+/-} 2.1 SD years) 14 TDC (12.3 years). MEG used localize characterize activity Go/No-Go task. Regional differences amplitude Go No-Go condition between versus were examined. Results: In the visual cue presented condition, participants showed significantly increased primary motor (MI) cortex TDC. A trend towards decreased orbitofrontal also found stop errors condition. Conclusion: Our preliminary small suggests within regions be altered Task performance, as an imaging tool sensitive detecting such differences.
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