Using High Frequency Transcranial Random Noise Stimulation to Modulate Face Memory Performance in Younger and Older Adults: Lessons Learnt From Mixed Findings.

摘要: High-frequency transcranial random noise stimulation (tRNS) has been shown to improve a range of cognitive and perceptual abilities. Here we sought examine the effects single session tRNS targeted at ventrolateral prefrontal cortices (VLPFC) on face memory in younger older adults. To do so, conducted three experiments. In Experiment 1, found that adults receiving active outperformed those sham (i.e., using between-participant factor for condition; 1). This effect was not observed object (car memory) (Experiment 2), indicating is general effect. 3, replicate 1 different design (within-participant – or same individual) extend study by including adult participants. contrast relative reduced performance both We also degree decline condition predicted baseline ability, with higher performing participants showing largest decreases performance. Overall, results indicate VLPFC modulates memory, but there may be protocol specific moderators this discuss these findings context broader literature importance individual variation outcome non-invasive brain intervention approaches. conclude while have potential as an approach, generalizing from experiment studies wide application risky caution should adopted interpreting findings.