Histopathologically verified non-vascular optic nerve lesions in Denmark 1940-99.

摘要: . Purpose: To evaluate the distribution in Denmark of histologically verified optic nerve lesions according to histological diagnosis, gender and age during a period 60 years calculate frequency possible changes observation period. Methods: All reported at Eye Pathology Institute, University Copenhagen, 1940–99 were investigated. similar all pathological departments 1974–99 also investigated. Results: The number identified totalled 313 298 patients. histopathological was seen have increased significantly over last 25 years, present, an average 12 per year are recorded. Lesions children represented 42% (130). percentage suffered by remained constant throughout period. Benign tumours constituted 33% (44) total adults 61% (62) children. Frequencies glioma sheath meningioma 25 years. Subjects presenting with exhibited significant difference presentation: mean women presentation be 48.8 years, while men 29.7 years. most frequent lesion invasion from malignant uveal melanoma. Conclusion: Histologically diagnosed rare consist primarily tumours. increase 25 years is due benign