Trans-Generational Effect of Maternal Lactation during Pregnancy: A Holstein Cow Model

摘要: Epigenetic regulation in mammals begins the first stages of embryogenesis. This prenatal programming determines, part, phenotype expression adult life. Some species, particularly dairy cattle, are conceived during maternal lactation, which is a period large energy and nutrient needs. Under these circumstances, embryo fetal development compete for nutrients with mammary gland, may affect predetermine at adulthood. Data from specialized breed were used to determine transgenerational effect when coincides lactation. Longitudinal phenotypic data milk yield (kg), ratio fat-protein content lifespan (d) 40,065 cows adjusted environmental genetic effects using Bayesian framework. Then, different circumstances was determined on residuals. The maternal-related 1) presence 2) level, 3) occurrence mastitis Females born mothers that lactating while pregnant produced 52 kg (MonteCarlo standard error; MCs.e. = 0.009) less milk, lived 16 d (MCs.e. 0.002) shorter metabolically efficient (+0.42% fat/protein ratio; MCs.e.<0.001) than females whose life developed absence greater embryogenesis, larger negative programming, precluding offspring most productive fully express their potential additive merit Our provide substantial evidence pregnancy lactation coincide. Although this relatively low, it should not be ignored formulating rations cows. Furthermore, breeding, replacement, management strategies also take into account whether individuals because, otherwise, performance deviate what could expected.