Short Communication: Lower Baseline CD4 Count Is Associated with a Greater Propensity Toward Virological Failure in a Cohort of South African HIV Patients

摘要: Abstract The antiretroviral (ARV) service at Edendale Hospital in Pietermaritzburg, KwaZulu-Natal, South Africa has initiated more than 9,000 adults on therapy since 2004; however, virological outcomes among this patient cohort have not been systematically assessed. We conducted a retrospective chart review of patients initiating ARVs recent years the roll-out to determine efficacy program. Clinic records were randomly selected for who had between January 2009 and December 2012. Demographic data collected. Virological failure was defined as achieve plasma viral load (VL) <25 copies/ml after 6–12 months ARV initiation or ≥2 consecutive HIV-RNA VLs ≥400 following suppression copies/ml. Records 228 individuals reviewed. Twenty-one (9%) experienced necessitating regimen change. median (interquartile range, IQR) duration exposure 19 ...