The Potential Role of Nitric Oxide in Halting Cancer Progression Through Chemoprevention

作者: Huzefa Vahora , Munawwar Ali Khan , Usama Alalami , Arif Hussain

DOI: 10.15430/JCP.2016.21.1.1

关键词:

摘要: Nitric oxide (NO) in general plays a beneficial physiological role as vasorelaxant and the of NO is decided by its concentration present environments. either facilitates cancer-promoting characters or act an anti-cancer agent. The dilemma this regard still remains unanswered. This review summarizes recent information on carcinogenesis tumor progression, well dietary chemopreventive agents which have NO-modulating properties with safe cytotoxic profile. Understanding molecular mechanisms cross-talk modulating effect these can allow us to develop better therapeutic strategies for cancer treatment.

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