Homopetasinic acid isolated from Diaporthe sp. strain 1308-05
作者： Atsushi Ito , Ikuya Kumagai , Miku Maruyama , Hayato Maeda , Akio Tonouchi
DOI: 10.1016/J.TETLET.2016.01.095
关键词:
摘要: Abstract Homopetasinic acid (1) was isolated from fungi of the Diaporthe sp. strain 1308-05. NMR spectroscopic structural analysis revealed a petasol (3) substructure and (4E,6E)-7-carboxy-3-hydroxy-2-methylhepta-4,6-dienoate side chain. The absolute configuration moiety established by specific rotation value after basic hydrolysis. (2′S,3′S)-configuration chain determined empirical methods as well comparison spectral data with related model compounds. structure on basis ECD analyses involving theoretical calculations. biological activities 1 are also discussed.
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