CHIMERIC POLYPEPTIDE, VACCINE AGAINST BABESIOSIS, IMMUNIZATION METHODS, DETECTION METHODS AND KIT.

作者: Silvina Elizabeth Wilkowsky , José Manuel Jaramillo Ortiz , Maria Paula Del Medico Zajac , Gabriela Calamante

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摘要: A chimeric polypeptide containing a fragment of MSA-2c antigen bound to RAP-1 HSP20 antigen, where the antigens are Babesia genus parasite. For example, may be represented by an amino acid sequence which contains at least 89% identity in relation SEQ ID N° 1. It shows composition for vaccine against babesiosis, immunization methods and detection methods.

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José Manuel Jaramillo Ortiz, María Paula Del Médico Zajac, Flavia Adriana Zanetti, María Paula Molinari, María José Gravisaco, Gabriela Calamante, Silvina Elizabeth Wilkowsky, Vaccine strategies against Babesia bovis based on prime-boost immunizations in mice with modified vaccinia Ankara vector and recombinant proteins Vaccine. ,vol. 32, pp. 4625- 4632 ,(2014) , 10.1016/J.VACCINE.2014.06.075
José Manuel Jaramillo Ortiz, María Paula Molinari, María José Gravisaco, Martina Soledad Paoletta, Valeria Noely Montenegro, Silvina Elizabeth Wilkowsky, Evaluation of different heterologous prime-boost immunization strategies against Babesia bovis using viral vectored and protein-adjuvant vaccines based on a chimeric multi-antigen. Vaccine. ,vol. 34, pp. 3913- 3919 ,(2016) , 10.1016/J.VACCINE.2016.05.053