Thiotaurine Protects Mouse Cerebellar Granule Neurons from Potassium Deprivation-Induced Apoptosis by Inhibiting the Activation of Caspase-3
作者： Jessica Dragotto , Elisabetta Capuozzo , Mario Fontana , Armando Curci , Maria Teresa Fiorenza
DOI: 10.1007/978-3-319-15126-7_41
关键词:
摘要: Taurine (2-aminoethanesulphonic acid) is an endogenous amino acid that has a number of protective roles in most mammalian cells, including modulation cytoplasmic calcium levels, antioxidant effects and protection against mitochondrial dysfunction endoplasmic reticulum stress associated with neurological disorders. Thiotaurine (2-aminoethane thiosulfonate), molecule structurally related to hypotaurine taurine, counteracts the damaging effect oxidants prevents apoptosis human neutrophils.
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