Taurine and Its Neuroprotective Role
作者： Neeta Kumari , Howard Prentice , Jang-Yen Wu
DOI: 10.1007/978-1-4614-6130-2_2
关键词:
摘要: Taurine plays multiple roles in the CNS including acting as a neuro-modulator, an osmoregulator, regulator of cytoplasmic calcium levels, trophic factor development, and neuroprotectant. In neurons taurine has been shown to prevent mitochondrial dysfunction protect against endoplasmic reticulum (ER) stress associated with neurological disorders. cortical culture protects excitotoxicity through reversing increase levels key ER signaling components eIF-2-alpha cleaved ATF6. The role communication between mitochondrion is also important examples are presented protection by together prevention subsequent initiated apoptosis.
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