Melanocytic Neoplasms I: Molecular Diagnosis
作者： Pedram Gerami , Bryan Gammon , Michael J. Murphy
DOI: 10.1007/978-1-60761-171-4_5
关键词:
摘要: There are many possible indications and potential uses for molecular diagnostic techniques in the evaluation management of melanocytic neoplasms. These include: (a) identification better diagnostic, staging, prognostic markers; (b) discovery novel therapeutic targets; (c) development a classification scheme, with to stratify melanomas into subtypes which have similar pathogenesis, prognosis, treatment responses; (d) determination patterns genetic deletions and/or gains that associated different clinical outcomes patients metastatic melanoma; (e) an improvement our ability accurately classify lesions currently considered morphologically ambiguous, such as atypical Spitz tumors; (f) individuals populations at high-risk melanoma development; (g) application testing help identify candidates requiring more comprehensive screening.
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