Xanthogranulomatous pancreatitis mimicking a malignant cystic tumor of the pancreas: Report of a case

摘要: Xanthogranulomatous pancreatitis (XGP) is a rare inflammatory disease of the pancreas. A correct diagnosis usually made only after pathological examination. 76-year-old man was referred to our hospital for investigation erythroderma, muscle weakness, and weight loss. We suspected dermatomyositis as paraneoplastic phenomenon investigated accordingly. Computed tomography showed cystic lesion encapsulated by thick wall in pancreatic body. On magnetic resonance imaging, had low intensity on T1-weighted images heterogeneously high T2-weighted images. (18)F-Fluorodeoxyglucose positron emission abnormal uptake with maximum standardized value 9.1. Based these findings, we preoperative intraductal papillary-mucinous carcinoma performed distal pancreatectomy. Macroscopically, cyst surrounded yellow-tan mass an unclear border, filled hemorrhagic necrotic tissue. Microscopically, contained aggregation many foamy histiocytes, lymphocytes, plasma cells. These microscopic findings were consistent xanthogranulomatous inflammation, diagnosed XGP. Although it benign lesion, XGP should nevertheless be considered differential lesions