Role of Substrates and Products of PI 3-kinase in Regulating Activation of Rac-Related Guanosine Triphosphatases by Vav
作者： Jaewon Han , Katherine Luby-Phelps , Balaka Das , Xiaodong Shu , Yi Xia
DOI: 10.1126/SCIENCE.279.5350.558
关键词:
摘要: Mitogen stimulation of cytoskeletal changes and c-jun amino-terminal kinases is mediated by Rac small guanine nucleotide-binding proteins. Vav, a guanosine diphosphate (GDP)–…
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Alex Toker, Lewis C. Cantley, Signalling through the lipid products of phosphoinositide-3-OH kinase Nature. ,vol. 387, pp. 673- 676 ,(1997) , 10.1038/42648
M Hyvönen, Maria J Macias, Michael Nilges, Hartmut Oschkinat, M Saraste, Matthias Wilmanns, Structure of the binding site for inositol phosphates in a PH domain. The EMBO Journal. ,vol. 14, pp. 4676- 4685 ,(1995) , 10.2210/PDB1BTN/PDB
M Raab, M Yamamoto, C E Rudd, The T-cell antigen CD5 acts as a receptor and substrate for the protein-tyrosine kinase p56lck. Molecular and Cellular Biology. ,vol. 14, pp. 2862- 2870 ,(1994) , 10.1128/MCB.14.5.2862
Pablo Rodriguez-Viciana, Patricia H Warne, Asim Khwaja, Barbara M Marte, Darryl Pappin, Pamela Das, Michael D Waterfield, Anne Ridley, Julian Downward, Role of Phosphoinositide 3-OH Kinase in Cell Transformation and Control of the Actin Cytoskeleton by Ras Cell. ,vol. 89, pp. 457- 467 ,(1997) , 10.1016/S0092-8674(00)80226-3
Tassie L. Collins, Marcel Deckert, Amnon Altman, Views on Vav Immunology Today. ,vol. 18, pp. 221- 225 ,(1997) , 10.1016/S0167-5699(97)01037-2
T. Joneson, M. A. White, M. H. Wigler, D. Bar-Sagi, Stimulation of Membrane Ruffling and MAP Kinase Activation by Distinct Effectors of RAS Science. ,vol. 271, pp. 810- 812 ,(1996) , 10.1126/SCIENCE.271.5250.810
Matthew J. Hart, Alessandra Eva, Tony Evans, Stuart A. Aaronson, Richard A. Cerione, Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product Nature. ,vol. 354, pp. 311- 314 ,(1991) , 10.1038/354311A0
Marcel Deckert, Sophie Tartare-Deckert, Clément Couture, Tomas Mustelin, Amnon Altman, Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product. Immunity. ,vol. 5, pp. 591- 604 ,(1996) , 10.1016/S1074-7613(00)80273-3
Piero Crespo, Kornel E. Schuebel, Amy A. Ostrom, J. Silvio Gutkind, Xosé R. Bustelo, Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product Nature. ,vol. 385, pp. 169- 172 ,(1997) , 10.1038/385169A0
Ian P Whitehead, Sharon Campbell, Kent L Rossman, Channing J Der, DBL FAMILY PROTEINS Biochimica et Biophysica Acta. ,vol. 1332, ,(1997) , 10.1016/S0304-419X(96)00040-6