摘要: A new study in mice shows that sarcolipin, a small, regulatory protein of the intracellular calcium pump (SERCA) skeletal muscle, is part nonshivering thermogenic mechanism for regulating both core body temperature and energy balance (pages 1575–1579).
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sci-hub.se 参考文章(13)
Leslie P. Kozak, Robert A. Koza, The genetics of brown adipose tissue. Progress in Molecular Biology and Translational Science. ,vol. 94, pp. 75- 123 ,(2010) , 10.1016/B978-0-12-375003-7.00004-2
Alexey E. Alekseev, Santiago Reyes, Satsuki Yamada, Denice M. Hodgson-Zingman, Srinivasan Sattiraju, Zhiyong Zhu, Ana Sierra, Marina Gerbin, William A. Coetzee, David J. Goldhamer, Andre Terzic, Leonid V. Zingman, Sarcolemmal ATP-Sensitive K+ Channels Control Energy Expenditure Determining Body Weight Cell Metabolism. ,vol. 11, pp. 58- 69 ,(2010) , 10.1016/J.CMET.2009.11.009
Lei Cao, Eugene Y. Choi, Xianglan Liu, Adam Martin, Chuansong Wang, Xiaohua Xu, Matthew J. During, White to Brown Fat Phenotypic Switch Induced by Genetic and Environmental Activation of a Hypothalamic-Adipocyte Axis Cell Metabolism. ,vol. 14, pp. 324- 338 ,(2011) , 10.1016/J.CMET.2011.06.020
Rea P. Anunciado-Koza, Jingying Zhang, Jozef Ukropec, Sudip Bajpeyi, Robert A. Koza, Richard C. Rogers, William T. Cefalu, Randall L. Mynatt, Leslie P. Kozak, Inactivation of the mitochondrial carrier SLC25A25 (ATP-Mg2+/Pi transporter) reduces physical endurance and metabolic efficiency in mice. Journal of Biological Chemistry. ,vol. 286, pp. 11659- 11671 ,(2011) , 10.1074/JBC.M110.203000
Leslie P. Kozak, Brown Fat and the Myth of Diet-Induced Thermogenesis Cell Metabolism. ,vol. 11, pp. 263- 267 ,(2010) , 10.1016/J.CMET.2010.03.009
Naresh C Bal, Santosh K Maurya, Danesh H Sopariwala, Sanjaya K Sahoo, Subash C Gupta, Sana A Shaikh, Meghna Pant, Leslie A Rowland, Eric Bombardier, Sanjeewa A Goonasekera, A Russell Tupling, Jeffery D Molkentin, Muthu Periasamy, Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals Nature Medicine. ,vol. 18, pp. 1575- 1579 ,(2012) , 10.1038/NM.2897
Sven Enerbäck, Human Brown Adipose Tissue Cell Metabolism. ,vol. 11, pp. 248- 252 ,(2010) , 10.1016/J.CMET.2010.03.008
Pontus Boström, Jun Wu, Mark P. Jedrychowski, Anisha Korde, Li Ye, James C. Lo, Kyle A. Rasbach, Elisabeth Almer Boström, Jang Hyun Choi, Jonathan Z. Long, Shingo Kajimura, Maria Cristina Zingaretti, Birgitte F. Vind, Hua Tu, Saverio Cinti, Kurt Højlund, Steven P. Gygi, Bruce M. Spiegelman, A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis Nature. ,vol. 481, pp. 463- 468 ,(2012) , 10.1038/NATURE10777
M. Asahi, Y. Sugita, K. Kurzydlowski, S. De Leon, M. Tada, C. Toyoshima, D. H. MacLennan, Sarcolipin regulates sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) by binding to transmembrane helices alone or in association with phospholamban Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 5040- 5045 ,(2003) , 10.1073/PNAS.0330962100
Wendy S. SMITH, Robert BROADBRIDGE, J. Malcolm EAST, Anthony G. LEE, Sarcolipin uncouples hydrolysis of ATP from accumulation of Ca2+ by the Ca2+-ATPase of skeletal-muscle sarcoplasmic reticulum. Biochemical Journal. ,vol. 361, pp. 277- 286 ,(2002) , 10.1042/BJ3610277