作者: G. Cutroneo , G. Anastasi , N. Donadio , A. Favaloro , A. Micali
DOI: 10.1159/000063706
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摘要: Focal contacts are systems of adherens junctions the cell-extracellular matrix type, which allow transfer fundamental signals from extracellular to nuclear compartments, capable regulating adhesion, proliferation, migration and differentiation cells. Recently, many authors have concentrated their attention on epitheliomesenchymal interactions guide organogenesis dental germ, identifying numerous growth factors having inner enamel epithelial cells organ as a target. Given that two cellular compartments in tooth germ separated by basal membrane an matrix, touches it, we wanted evaluate presence focal through identification talin vinculin, proteins actin-associated protein complex. In this study utilized hemimandibles young Wistar rats extracted related odontogenic organs present at apical end. Specimens processed with antibody against vinculin talin. Results show these junctional system poles both suggesting putative epithelial-mesenchymal interactions, other than marker molecules, may use for transmission signals.