Antimutagenic and antioxidant/prooxidant activity of quercetin.

摘要: The present study has been performed to evaluate the antimutagenic activity of quercetin, ascorbic acid and their combination against an oxidative mutagen. An effort was also made correlate this in vitro antioxidant these agents. Antimutagenicity testing done Ames Salmonella Assay system using typhimurium TA102 t-butylhydroperoxide as In scavenging tested for DPPH free radical, superoxide anion, hydrogen peroxide hydroxyl radical specific test systems. Quercetin (0.5-8 nmole/plate) (0.1-100 micromole/plate) showed significant effect. (4 8 when combined with (500 increase activity. quercetin better than all systems used. indicated that not solely accountable by its nature. However, correlated well