Autonomic Dysfunction Is the Motor of Chronic Critical Illness

作者: A. Toner , J. Whittle , G. L. Ackland

DOI: 10.1007/978-3-642-35109-9_16

关键词:

摘要: Many of the insults that lead to critical illness, such as sepsis, trauma and major surgery, either cause, or are perhaps consequence of, profound alterations in autonomic nervous system control. Several cardinal features chronic illness – regardless etiology support assertion dysfunction is a core mechanism underlying development perpetuation multiorgan failure. By reconsidering spectrum encompasses, we explore pivotal multi-faceted impact exerted by aberrant control illness.

参考文章(51)
Jason T. Davis, Fangwen Rao, Dalal Naqshbandi, Maple M. Fung, Kuixing Zhang, Andrew J. Schork, Caroline M. Nievergelt, Michael G. Ziegler, Daniel T. O'Connor, Autonomic and Hemodynamic Origins of Pre-Hypertension: Central Role of Heredity Journal of the American College of Cardiology. ,vol. 59, pp. 2206- 2216 ,(2012) , 10.1016/J.JACC.2012.02.040
Kevin J Tracey, Understanding immunity requires more than immunology Nature Immunology. ,vol. 11, pp. 561- 564 ,(2010) , 10.1038/NI0710-561
Gau-Jun Tang, Yu Ru Kou, You Shuei Lin, Peripheral neural modulation of endotoxin-induced hyperventilation Critical Care Medicine. ,vol. 26, pp. 1558- 1563 ,(1998) , 10.1097/00003246-199809000-00024
Patrick R. Norris, Asli Ozdas, Hanqing Cao, Anna E. Williams, Frank E. Harrell, Judith M. Jenkins, John A. Morris, Cardiac Uncoupling and Heart Rate Variability Stratify ICU Patients by Mortality: A Study of 2088 Trauma Patients Annals of Surgery. ,vol. 243, pp. 804- 814 ,(2006) , 10.1097/01.SLA.0000219642.92637.FD
Rainer H. Straub, Hans‐Jörg Linde, Daniela N. Männel, Jürgen Schölmerich, Werner Falk, A bacteria-induced switch of sympathetic effector mechanisms augments local inhibition of TNF-α and IL-6 secretion in the spleen The FASEB Journal. ,vol. 14, pp. 1380- 1388 ,(2000) , 10.1096/FASEBJ.14.10.1380
Jasper Truijen, Shyrin C.A.T. Davis, Wim J. Stok, Yu-Sok Kim, David J. van Westerloo, Marcel Levi, Tom van der Poll, Berend E. Westerhof, John M. Karemaker, Johannes J. van Lieshout, Baroreflex sensitivity is higher during acute psychological stress in healthy subjects under β-adrenergic blockade. Clinical Science. ,vol. 120, pp. 161- 167 ,(2011) , 10.1042/CS20100137
Giora Landesberg, Yellena Vesselov, Sharon Einav, Sergei Goodman, Charles L. Sprung, Charles Weissman, Myocardial ischemia, cardiac troponin, and long-term survival of high-cardiac risk critically ill intensive care unit patients. Critical Care Medicine. ,vol. 33, pp. 1281- 1287 ,(2005) , 10.1097/01.CCM.0000166607.22550.87
Christian Meisel, Andreas Meisel, Suppressing immunosuppression after stroke. The New England Journal of Medicine. ,vol. 365, pp. 2134- 2136 ,(2011) , 10.1056/NEJMCIBR1112454
Dennis C. Gore, Robert R. Wolfe, Hemodynamic and metabolic effects of selective β1 adrenergic blockade during sepsis Surgery. ,vol. 139, pp. 686- 694 ,(2006) , 10.1016/J.SURG.2005.10.010