The effect of diet enriched with rapeseed meal on endogenous thiouracil contents in urine of calves.
作者： B. Woźniak , S. Witek , I. Matraszek-Żuchowska , B. Sell , A. Posyniak
DOI: 10.1016/J.RVSC.2020.10.021
关键词:
摘要: Abstract Thiouracil (TU) is a representative of group thyreostatics, orally active drugs that can be used to increase the weight cattle before slaughter. The use thyreostats in animal production has been banned European Union since 1981. Systematic detection low concentrations thiouracil urine livestock acknowledged endogenous origin due Brassicaceae plants diet. purpose study was determine effect diet enriched with rapeseed meal on contents calves. Two groups calves different age were subjected rapeseed-supplemented First (n = 6, 6 months) received maximum authorized content (30%) diet, second (n = 2, 2 months) after adaptation solid food and rapeseed, exceeding recommended dose 10%. During experiments, samples faeces collected analyzed by using accredited LC-MS/MS method. allowed did not influenced concentration calves' (
sci-hub.st 参考文章(12)
Barbara Wozniak, Iwona Matraszek Zuchowska, Jan Zmudzki, Piotr Jedziniak, Beata Korycinska, Katarzyna Sielska, Sebastian Witek, Alicja Klopot, Liquid chromatography tandem mass spectrometry with ion trap and triple quadrupole analyzers for determination of thyreostatic drugs in urine and muscle tissue. Analytica Chimica Acta. ,vol. 700, pp. 155- 166 ,(2011) , 10.1016/J.ACA.2011.02.021
Julie A. L. Kiebooms, Jella Wauters, Julie Vanden Bussche, Kurt Houf, Paul De Vos, Stefanie Van Trappen, Ilse Cleenwerck, Lynn Vanhaecke, Thiouracil-Forming Bacteria Identified and Characterized upon Porcine In Vitro Digestion of Brassicaceae Feed Applied and Environmental Microbiology. ,vol. 80, pp. 7433- 7442 ,(2014) , 10.1128/AEM.02370-14
Barbara Wozniak, Sebastian Witek, Iwona Matraszek-Zuchowska, Jan Zmudzki, Development and Application of LC-MS/MS Method for the Detection of Naturally Occurring Thiouracil in Milk Samples Food Analytical Methods. ,vol. 7, pp. 1588- 1597 ,(2014) , 10.1007/S12161-014-9793-Y
G. Pinel, S. Mathieu, N. Cesbron, D. Maume, H. F. De Brabander, F. Andre, B. Le Bizec, Evidence that urinary excretion of thiouracil in adult bovine submitted to a cruciferous diet can give erroneous indications of the possible illegal use of thyrostats in meat production. Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment. ,vol. 23, pp. 974- 980 ,(2006) , 10.1080/02652030600806370
J. Vanden Bussche, H. Noppe, K. Verheyden, K. Wille, G. Pinel, B. Le Bizec, H.F. De Brabander, Analysis of thyreostats: A history of 35 years Analytica Chimica Acta. ,vol. 637, pp. 2- 12 ,(2009) , 10.1016/J.ACA.2008.08.027
J. Vanden Bussche, L. Vanhaecke, Y. Deceuninck, K. Wille, K. Bekaert, B. Le Bizec, H.F. De Brabander, Ultra-high performance liquid chromatography coupled to triple quadrupole mass spectrometry detection of naturally occurring thiouracil in urine of untreated livestock, domesticated animals and humans. Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment. ,vol. 28, pp. 166- 172 ,(2011) , 10.1080/19440049.2010.544681
Terenzio Bertuzzi, Silvia Rastelli, Annalisa Mulazzi, Amedeo Pietri, Trace Monitoring of Goitrin and Thiouracil in Milk and Cheese Food Analytical Methods. ,vol. 9, pp. 2952- 2959 ,(2016) , 10.1007/S12161-016-0483-9
Jella Wauters, Julie Vanden Bussche, Bruno Le Bizec, Julie A. L. Kiebooms, Gaud Dervilly-Pinel, Stéphanie Prevost, Barbara Wozniak, Saskia S. Sterk, Dag Grønningen, D. Glenn Kennedy, Sandra Russell, Philippe Delahaut, Lynn Vanhaecke, Toward a new European threshold to discriminate illegally administered from naturally occurring thiouracil in livestock. Journal of Agricultural and Food Chemistry. ,vol. 63, pp. 1339- 1346 ,(2015) , 10.1021/JF504475F
N. Babu, Theoretical Study of Stability, Tautomerism, Equilibrium Constants (pKT) of 2-Thiouracil in Gas Phase and Different Solvents (Water and Acetonitrile) by the Density Functional Theory Method American Chemical Science Journal. ,vol. 3, pp. 137- 150 ,(2013) , 10.9734/ACSJ/2013/2905
J. Wauters, L. Van Meulebroek, E. Fichant, P. Delahaut, L. Vanhaecke, Discrimination between Synthetically Administered and Endogenous Thiouracil Based on Monitoring of Urine, Muscle, and Thyroid Tissue: An in Vivo Study in Young and Adult Bovines Journal of Agricultural and Food Chemistry. ,vol. 65, pp. 6231- 6239 ,(2017) , 10.1021/ACS.JAFC.7B01920