Mutations at Amino Acid Position 315 of the katG Gene Are Associated with High-Level Resistance to Isoniazid, Other Drug Resistance, and Successful Transmission of Mycobacterium tuberculosis in The Netherlands
作者： Dick van Soolingen , Petra E. W. de Haas , H. Rogier van Doorn , Ed Kuijper , Heinz Rinder
DOI: 10.1086/317598
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摘要: … mutations at aa 315 of the katG gene of INH-resistant strains … Ser315Thr substitutions in the katG gene were predominant (… strains with mutations at aa 315 of katG are more likely to gain …
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